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  • Scientific publication
22/10/2025

Exploring the role of ENT1 in T-cell metabolism for improved cancer immunotherapy

TransCure bioServices is proud to contribute to groundbreaking research uncovering the role of the ENT1 transporter in the regulation of T-cell activity within the tumor microenvironment.

This study published by Theodore Sanders and colleagues in Nature Immunology sheds light on how metabolic pathways influence immune responses, paving the way for more effective immunotherapy strategies.

Our CD34+ engrafted humanized mouse models enabled in-depth characterization of the immune mechanisms taking place in the tumor compartment, further demonstrating their value in translational immuno-oncology research.

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